General Adaptation Syndrome


Selye's General Adaptation Syndrome

When Hans Selye was experimenting on rats by inflicting stress them either by injecting them with hormones or chemicals, making surgical incisions or exposing them to extreme temperatures, he noticed that the rats were all displaying the same group of symptoms. At first he believed that he had discovered a new hormone1; however, several years of further testing by injecting the rats with other substances, such as formaldehyde, revealed the same results. Even exposure to cold, cutting their spinal cords and forced exercise produced the same effects. The effects occurred in a predictable sequence that is now known as the General Adaptation Syndrome2 (GAS).

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