it's very interesting how they did not monitor people who take calcium plus vitamin D. some great comments in the comments section :)
That's amazing. I was just working on formatting a large article by Robin M. Daly and Peter R. Ebelingon on this subject (excess vitamin D and health risk) that mentions this meta analysis. I'll link it here once it is up. Should shed a lot of light on this.
Unfortunately this review was published before the [meta-analysis discussed in the article, Effect of calcium supplements on risk of myocardial infarction and cardiovascular events, was published in full form…only the abstract was available which the authors point out. However, in light of the supposed reaction to this analysis and other evidence the authors stated:
When evaluating whether calcium supplements adversely affect vascular disease, it is important to consider that total calcium intakes may exceed 2,000 to 2,500 mg per day (1,000–1,200 mg/d supplemental calcium plus 800–1,000 mg/d dietary calcium). At these levels, there may well be some cause for concern, but several important questions still remain. Is the level of risk the same for all women or is it greatest in those already at high risk of CVD? Does the level of risk vary by the type of calcium supplement used, particularly those that led to greater elevations of serum calcium
concentrations, and does the addition of vitamin D counteract this increased risk? Is there a threshold level of calcium above which intakes become detrimental to health? Although there is currently no evidence to support such a threshold, a recent study in healthy adult men and women aged 19 to 75 years which was designed to determine the level of dietary calcium to maintain neutral calcium balance, reported that the calcium requirements (or recommended dietary allowance) for men and women should be approximately 1035 mg/d . While some have questioned the balance-based approach used to estimate the average calcium requirements in this study , these findings provide some evidence that daily calcium requirements may be lower than previously estimated.
- Robin M. Daly and Peter R. Ebeling in "Is Excess Calcium Harmful to Health?"