Fish Oil

Common Fish Oil Questions Answered: A Baker's Dozen

Here at Ground Up strength you can find the answers to most common questions regarding fish oil in the various articles we have but we have some fairly heavy reading so you need to dig a bit to find the particular answer you're looking for. So I thought I'd write a blog post that provided simple answers to the most common questions about fish oil supplements. I will keep these answers short and to the point in a radical shift from my usual style although a few will be a bit longer for the purpose of clarity.

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Omega 3 Fatty Acids And Inflammation

Long chain fatty acids influence inflammation through a variety of mechanisms; many of these are mediated by, or at least associated with, changes in fatty acid composition of cell membranes. Changes in these compositions can modify membrane fluidity, cell signaling leading to altered gene expression, and the pattern of lipid mediator production. Cell involved in the inflammatory response are typically rich in the n-6 fatty acid arachidonic acid, but the contents of arachidonic acid and of the n-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can be altered through oral administration of EPA and DHA. Eicosanoids produced from arachidonic acid have roles in inflammation. EPA also gives rise to eicosanoids and these often have differing properties from those of arachidonic acid-derived eicosanoids. EPA and DHA give rise to newly discovered resolvins which are anti-inflammatory and inflammation resolving. Increased membrane content of EPA and DHA (and decreased arachidonic acid content) results in a changed pattern of production of eicosanoids and resolvins. Changing the fatty acid composition of cells involved in the inflammatory response also affects production of peptide mediators of inflammation (adhesion molecules, cytokines etc.). Thus, the fatty acid composition of cells involved in the inflammatory response influences their function; the contents of arachidonic acid, EPA and DHA appear to be especially important. The anti-inflammatory effects of marine Omega 3 PUFAs suggest that they may be useful as therapeutic agents in disorders with an inflammatory component.

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Fish Oil Quality

Fish oil paranoia is rampant right now.

Of course you do need to be careful what fish oil products you use. There is always some contaminated product floating around out there. Even some of the nutritional experts seem to be a little misled, however. Perhaps because they have more money than I it’s easy to get lazy and assume more expensive means better quality.

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