Antioxidants

Vitamin Enhanced Waters and Fruit Juice Beverages Analyzed for Polyphenol Antioxidant Capacity and Antioxidants per Calorie

Polyphenols have become a recent interest to health conscious individuals. As a result, beverages containing high concentrations of polyphenols are becoming increasingly popular. This is due to the health benefits that accompany polyphenol consumption, derived from their antioxidant properties [1]. Polyphenols have been found to inhibit reactive oxygen species formation and protect against coronary heart disease [2,3]. Polyphenols have also been reported to potentially inhibit the development of certain types of cancer, such as breast cancer, and slow tumor growth [4-8]. The fact that these polyphenols can help prevent chronic disease has prompted beverage manufacturers to produce drinks that boast antioxidant content and consumers may look to these beverages for consumption of antioxidants and nutrients. These include vitamin enhanced waters (VEWs) and a variety of fruit and berry juices.

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The Role of Phytonutrients Like Vitamin E and Beta-Carotene in Skin Health

Photodamage is known to occur in skin with exposure to sunlight, specifically ultraviolet (UV) radiation. Such damage includes inflammation, oxidative stress, breakdown of the extracellular matrix, and development of cancer in the skin. Sun exposure is considered to be one of the most important risk factors for both nonmelanoma and melanoma skin cancers. Many phytonutrients have shown promise as photoprotectants in clinical, animal and cell culture studies. In part, the actions of these phytonutrients are thought to be through their actions as antioxidants. In regard to skin health, phytonutrients of interest include vitamin E, certain flavonoids, and the carotenoids, ß-carotene, lycopene and lutein.

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Grape Polyphenols and Their Biological Activities

Grapes have a long and abundant history. During the ancient Greek and Roman civilizations, grapes were revered for their use in wine making. Nowadays, there are three main species of grapes: European grapes (Vitis vinifera), North American grapes (Vitis labrusca and Vitis rotundifolia) and French hybrids. Grapes are classified as table grapes, wine grapes (used in viniculture), raisin grapes, and so on, with edible seeds or seedless. People often enjoy the various grape products, such as fruit, raisins, juice and wine. Grape fruit contains various nutrient elements, such as vitamins, minerals, carbohydrates, edible fibers and phytochemicals. Polyphenols are the most important phytochemicals in grape because they possess many biological activities and health-promoting benefits [1–3]. The phenolic compounds mainly include anthocyanins, flavanols, flavonols, stilbenes (resveratrol) and phenolic acids [4–6]. Anthocyanins are pigments, and mainly exist in grape skins. Flavonoids are widely distributed in grapes, especially in seeds and stems, and principally contain (+)-catechins, (−)-epicatechin and procyanidin polymers. Anthocyanins are the main polyphenolics in red grapes, while flavan-3-ols are more abundant in white varieties [7–9].

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Vitamin E Update: Tocopherol and Tocotrienol

Vitamin E, like tocotrienols and tocopherols, is constituted of compounds essential for animal cells. Vitamin E is exclusively synthesized by photosynthetic eukaryotes and other oxygenic photosynthetic organisms such as cyanobacteria. In order to prevent lipid oxidation, the plants mainly accumulate tocochromanols in oily seeds and fruits or in young tissues undergoing active cell divisions. From a health point of view, at the moment there is a great interest in the natural forms of tocochromanols, because they are considered promising compounds able to maintain a healthy cardiovascular system and satisfactory blood cholesterol levels. Some evidence suggests that the potency of the antioxidant effects may differ between natural or synthetic source of tocochromanols (vitamin E).

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The Antioxidant Role of Glutathione and N-Acetyl-Cysteine Supplements and Exercise-Induced Oxidative Stress

An increase in exercise intensity is one of the many ways in which oxidative stress and free radical production has been shown to increase inside our cells. Effective regulation of the cellular balance between oxidation and antioxidation is important when considering cellular function and DNA integrity as well as the signal transduction of gene expression. Many pathological states, such as cancer, Parkinson's disease, and Alzheimer's disease have been shown to be related to the redox state of cells. In an attempt to minimize the onset of oxidative stress, supplementation with various known antioxidants has been suggested. Glutathione and N-acetyl-cysteine (NAC) are antioxidants which are quite popular for their ability to minimize oxidative stress and the downstream negative effects thought to be associated with oxidative stress.

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