Amino Acids

The following page list's the articles at Ground Up Strength concerning amino acids or that refer to amino acids.

What Are Amino Acids?

Amino acids are the individual building blocks of proteins. Proteins are a fundamental ingredient of all forms of life on Earth. They fuel and direct biochemical actions and provide the structure of our bodies. Proteins can act as cell to cell signalers (hormones and cytokines), molecular transporters, enzymes, neurotransmitters and a host of other functions. In fact, all major structural and functional actions in the body are carried out by proteins, including the passing of genetic information though DNA and RNA. When most of us think of protein, however we think of muscle. Muscle is the largest reservoir of protein in our bodies and the second largest store of energy, next to adipose tissue (fat). The muscle tissue of other animals is the largest source of protein in our diets.

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Dietary Supplement Ripoffs to Avoid: Amino Acid Pills

There is no long-term advantage for the strength trainee to taking expensive free form amino acid powders over simply ingesting whole proteins. However, if you do buy an amino acid powder (which I don't suggest) you expect it to contain single free form aminos acids, right?

Never trust the front label. Check the ingredients. The supplement rippoffs I am referring to are so-called amino acid capsules that actually contain overpriced whey or casein protein. Not free form single aminos but whole proteins compressed into a pill or put in a capsule. They will typically list an amino acid profile very prominently on the back of the label. This profile is nothing more than the typical amino acid yields of the whey or casein sources they use. When whey is used it is usually a mixture of whey protein concentrate or a mixture of concentrate and even cheaper non concentrated whey. Some may contain concentrates and isolates.

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Tryptophan Supplements: Do They Work and Are They Dangerous?

Many people, with or without any scientific evidence, are firmly convinced that the particular foods they eat have a direct influence on their mood, anxiety level and alertness. Perhaps the most well known manifestation of this belief is that certain foods make us sleepy, particularly those with high levels of the amino acid tryptophan. Turkey, at least in the US, is thought to cause sleepiness due to it's high level of tryptophan and this is said to explain why we are so desperate for a nap after Thanksgiving dinner.

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The Antioxidant Role of Glutathione and N-Acetyl-Cysteine Supplements and Exercise-Induced Oxidative Stress

An increase in exercise intensity is one of the many ways in which oxidative stress and free radical production has been shown to increase inside our cells. Effective regulation of the cellular balance between oxidation and antioxidation is important when considering cellular function and DNA integrity as well as the signal transduction of gene expression. Many pathological states, such as cancer, Parkinson's disease, and Alzheimer's disease have been shown to be related to the redox state of cells. In an attempt to minimize the onset of oxidative stress, supplementation with various known antioxidants has been suggested. Glutathione and N-acetyl-cysteine (NAC) are antioxidants which are quite popular for their ability to minimize oxidative stress and the downstream negative effects thought to be associated with oxidative stress.

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The Role Of Carnitine in Disease

Carnitine is a conditionally essential nutrient that plays a vital role in energy production and fatty acid metabolism. Vegetarians possess a greater bioavailability than meat eaters. Distinct deficiencies arise either from genetic mutation of carnitine transporters or in association with other disorders such as liver or kidney disease. Carnitine deficiency occurs in aberrations of carnitine regulation in disorders such as diabetes, sepsis, cardiomyopathy, malnutrition, cirrhosis, endocrine disorders and with aging. Nutritional supplementation of L-carnitine, the biologically active form of carnitine, is ameliorative for uremic patients, and can improve nerve conduction, neuropathic pain and immune function in diabetes patients while it is life-saving for patients suffering primary carnitine deficiency. Clinical application of carnitine holds much promise in a range of neural disorders such as Alzheimer's disease, hepatic encephalopathy and other painful neuropathies. Topical application in dry eye offers osmoprotection and modulates immune and inflammatory responses. Carnitine has been recognized as a nutritional supplement in cardiovascular disease and there is increasing evidence that carnitine supplementation may be beneficial in treating obesity, improving glucose intolerance and total energy expenditure.

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